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CURCUMIN-INFUSION: 

Yana Manolova, Vera Deneva, Liudmil Antonov, at al: The effect of the water on the curcumin tautomerism: A quantitative approach. In: Spectrochimica Acta. 132A, Nr. 1,  2014, S. 815–820. doi:10.1016/j.saa.2014.05.096.

Menon V, Sudheer A. Antioxidant and anti-inflammatory properties of curcumin. Adv. Exp. Med. Biol. 2007;595:105.

Madhu K, Chanda K, Saji MJ; Safety and efficacy of Curcuma longa extract in

the treatment of painful knee osteoarthritis: a randomized

placebo-controlled trial. Inflammopharmacology, Dezember 2012.

Cruz-Corres et al.: Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis. In: Clin Gastroenterol Hepatol. Aug;4(8), 2006, S. 1035–1038, PMID 16757216

Aggarwal et al.: Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in

breast cancer cells and inhibits lung metastasis of human breast cancer

in nude mice. In: Clin Cancer Res. Oct 15;11(20), 2005, S. 7490–7498, PMID 16243823

Hadi et al.: Putative mechanism for anticancer and apoptosis-inducing properties of plant-derived polyphenolic compounds. In: IUBMB Life. Sep;50(3), 2000, S. 167–171, PMID 11142343

Surh: Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances, Mutat Res. Jul 16;428(1-2), 1999, S. 305–327, PMID 10518003

Surh et al.: Molecular mechanisms underlying chemopreventive activities of anti-inflammatory

phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. In: Mutat Res. Sep 1, 2001, S. 480–481, 243–268, PMID 11506818

Kawamori et al.: Chemopreventive effect of curcumin, a naturally occurring anti-inflammatory agent, during the promotion/progression stages of colon cancer. In: Cancer Res. Feb 1;59(3), 1999, S. 597–601, PMID 9973206

Aggarawal et al.: Anticancer potential of curcumin: preclinical and clinical studies. In: Anticancer Res. Jan-Feb;23(1A), 2003, S. 363–398, PMID 12680238

PH Killian, E Kronski, K Michalik, O Barbieri, S Astigiano, CP Sommerhoff, U Pfeffer, AG Nerlich, BE Bachmeier: Curcumin Inhibits Prostate Cancer Metastasis in vivo by Targeting the Inflammatory Cytokines CXCL1 and -2. In: Carcinogenesis. 2012 Oct 5, PMID 23042094

B Bachmeier, AG Nerlich, CM Iancu, M Cilli, E Schleicher, R Vené, R Dell’Eva, M Jochum, A Albini, U Pfeffer: The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice. In: Cell Physiol Biochem. 2007;19(1-4), S. 137–152, PMID 17310108.

BE Bachmeier, IV Mohrenz, V Mirisola, E Schleicher, F Romeo, C Höhneke, M Jochum, AG Nerlich, U Pfeffer: Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB. In: Carcinogenesis, 2008 Apr;29(4), S. 779–789. Epub 2007 Nov 13, PMID 17999991.

Oh et al.: Curcumin inhibits osteoclastogenesis by decreasing receptor activator of nuclear

factor-kappaB ligand (RANKL) in bone marrow stromal cells. In: Mol Cells. Nov 30;26(5), 2008, S. 486–489, PMID 18719352.

Kim et al.: Curcumin protects against ovariectomy-induced bone loss and decreases osteoclastogenesis. In: J Cell Biochem. 2011 Jul 5, PMID 21732406.

Cuomo et al.: Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation. In: J Nat Prod. 2011 Apr 25;74(4), S. 664–669, PMID 21413691.

Belcaro et al.: Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis. In: Panminerva Med. (2010) Jun;52(2 Suppl 1), S. 55–62, PMID 20657536.

Kowluru et al.: Effects of curcumin on retinal oxidative stress and inflammation in diabetes. In: Nutr Metab (Lond). 2007 Apr 16;4, S. 8, PMID 17437639

JM Ringman et al.: A potential role of the curry spice curcumin in Alzheimer’s disease. In: Curr Alzheimer Res. 2005(2), S. 131–136; PMID 15974909; PMC 1702408 (freier Volltext).

K. T. Kim, M. J. Kim, D. C. Cho, S. H. Park, J. H. Hwang, J. K. Sung, H. J. Cho, Y. Jeon: The neuroprotective effect of treatment with curcumin in acute spinal cord injury: laboratory investigation. In: Neurologia medico-chirurgica. Band 54, Nummer 5, 2014, S. 387–394, ISSN 1349-8029. PMID 24477066.

W. H. Lee, C. Y. Loo, M. Bebawy, F. Luk, R. S. Mason, R. Rohanizadeh: Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century. In: Current neuropharmacology. Band 11, Nummer 4, Juli 2013, S. 338–378, ISSN 1570-159X. doi:10.2174/1570159X11311040002. PMID 24381528. PMC 3744901 (freier Volltext).

J. M. Witkin, S. Leucke, L. K. Thompson, R. A. Lynch, C. Ding, B. Heinz, J. T. Catlow, S. D. Gleason, X. Li: Further evaluation of the neuropharmacological determinants of the antidepressant-like effects of curcumin. In: CNS & neurological disorders drug targets. Band 12, Nummer 4, Juni 2013, S. 498–505, ISSN 1996-3181. PMID 23574162.

K. M. Choudhary, A. Mishra, V. V. Poroikov, R. K. Goel: Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice. In: European journal of pharmacology. Band 704, Nummer 1–3, März 2013, S. 33–40, ISSN 1879-0712. doi:10.1016/j.ejphar.2013.02.012. PMID 23461849.

S. K. Kulkarni, A. Dhir: An overview of curcumin in neurological disorders. In: Indian journal of pharmaceutical sciences. Band 72, Nummer 2, März 2010, S. 149–154, ISSN 1998-3743. doi:10.4103/0250-474X.65012. PMID 20838516. PMC 2929771 (freier Volltext).

S. T. Hasan, J. M. Zingg, P. Kwan, T. Noble, D. Smith, M. Meydani: Curcumin modulation of high fat diet-induced atherosclerosis and steatohepatosis in LDL receptor deficient mice. In: Atherosclerosis. Band 232, Nummer 1, Januar 2014, S. 40–51, ISSN 1879-1484. doi:10.1016/j.atherosclerosis.2013.10.016. PMID 24401215.

Y. Öner-İyidoğan, H. Koçak, M. Seyidhanoğlu, F. Gürdöl, A. Gülçubuk, F. Yildirim, A. Çevik, M. Uysal: Curcumin prevents liver fat accumulation and serum fetuin-A increase in rats fed a high-fat diet. In: Journal of Physiology and Biochemistry. Band 69, Nummer 4, Dezember 2013, S. 677–686, ISSN 1877-8755. doi:10.1007/s13105-013-0244-9. PMID 23430567.

P. G. Bradford: Curcumin and obesity. In: BioFactors (Oxford, England). Band 39, Nummer 1, 2013 Jan-Feb, S. 78–87, ISSN 1872-8081. doi:10.1002/biof.1074. PMID 23339049. (Review).

D. W. Zhang, M. Fu, S. H. Gao, J. L. Liu: Curcumin and diabetes: a systematic review. In: Evidence-based complementary and alternative medicine : eCAM. Band 2013, 2013, S. 636053, ISSN 1741-427X. doi:10.1155/2013/636053. PMID 24348712. PMC 3857752 (freier Volltext). (Review).

Tonnesen et al.: Studies of curcumin and curcuminoids XXVII. Cyclodextrin complexation: Solubility, chemical and photochemical stability. In: Int J Pharm, 2002, 244, S. 127–135, PMID 12204572

Pan et al.: Biotransformation of curcumin through reduction and glucuronidation in mice. In: Drug Metab Dispos, 1999, 27, S. 486–494, PMID 10101144

Cuomo et al.: Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation. In: J Nat Prod. 2011, Apr 25;74(4), S. 664–669, PMID 21413691

Gupta & Dixit: Bioavailability enhancement of curcumin by complexation with phosphatidyl choline. In: J Pharm Sci. 2011 May;100(5), S. 1987–1995, PMID 21374628

Henrotin, Y., F. Priem, and A. Mobasheri: Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management. Springerplus, 2013. 2(1): S. 56

Anand, P.; Kunnumakkara, A. B.; Newman, R. A.; Aggarwal, B. B. (2007). Bioavailability of curcumin: problems and promises. In: Molecular Pharmaceutics 4 (6): 807–818.

Marczylo, T. H.; Verschoyle, R. D.; Cooke, D. N.; Morazzoni, P.; Steward, W. P.; Gescher, A. J. (2007). Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine. In: Cancer Chemotherapy and Pharmacology 60 (2): 171–177.

 

VITAMIN C – HOCHDOSISINFUSION

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2. Davison G, Gleeson M. Influence of acute vitamin C and/or carbohydrate ingestion on hormonal, cytokine, and immune re- sponses to prolonged exercise. Int J Sport Nutr Exerc Metab. 2005 Oct;15(5):465-79.

3. Hemila H. Vitamin C and common cold incidence: a review of studies with subjects under heavy physical stress. Int J Sports Med. 1996 Jul;17(5):379-83.

4. Eguchi M, Miyazaki T, Masatsuji-Kato E, et al. Cytoprotection against ischemia-induced DNA cleavages and cell injuries in the rat liver by pro-vitamin C via hydrolytic conversion into ascorbate. Mol Cell Biochem. 2003 Oct;252(1-2):17-23.

5. Furumoto K, Inoue E, Nagao N, Hiyama E, Miwa N. Age-dependent telomere shortening is slowed down by enrichment of intra- cellular vitamin C via suppression of oxidative stress. Life Sci. 1998;63(11):935-48.

6. Loguercio C, Cuomo A, Tuccillo C, et al. Liver p53 expression in patients with HCV-related chronic hepatitis. J Viral Hepat. 2003 Jul;10(4):266-70.

7. Yokoo S, Furumoto K, Hiyama E, Miwa N. Slow-down of age-dependent telomere shortening is executed in human skin kerati- nocytes by hormesis-like-effects of trace hydrogen peroxide or by anti-oxidative effects of pro-vitamin C in common concurrently with reduction of intracellular oxidative stress. J Cell Biochem. 2004 Oct 15;93(3):588-97.

8. Wintergerst ES, Maggini S, Hornig DH. Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. Ann Nutr Metab. 2006;50(2):85-94.

9. Hemila H. Vitamin C supplementation and respiratory infections: a systematic review. Mil Med. 2004 Nov;169(11):920-5.

10. Gorton HC, Jarvis K. The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infec- tions. J Manipulative Physiol Ther. 1999 Oct;22(8):530-3.

11. Hemila H, Douglas RM. Vitamin C and acute respiratory infections. Int J Tuberc Lung Dis. 1999 Sep;3(9):756-61.

12. Petersen EE, Magnani P. Efficacy and safety of vitamin C vaginal tablets in the treatment of non-specific vaginitis. A randomised, double blind, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol. 2004 Nov 10;117(1):70-5.

13. Salgueiro J, Zubillaga M, Goldman C, et al. Review article: is there a link between micronutrient malnutrition and Helicobacter pylori infection? Aliment Pharmacol Ther. 2004 Nov 15;20(10):1029-34.

14. Kim HJ, Kim MK, Chang WK, et al. Effect of nutrient intake and Helicobacter pylori infection on gastric cancer in Korea: a case- control study. Nutr Cancer. 2005;52(2):138-46.

15. Khaw KT, Bingham S, Welch A, et al. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition. Lancet. 2001 Mar 3;357(9257):657-63.

16. Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiolo- gy. 1992 May;3(3):194-202.

17. Nakata Y, Maeda N. Vulnerable atherosclerotic plaque morphology in apolipoprotein E-deficient mice unable to make ascorbic Acid. Circulation. 2002 Mar 26;105(12):1485-90.

18. Kim DS, Lee MS, Kim YS, et al. Effect modification by vitamin C on the relation between gastric cancer and Helicobacter pylori. Eur J Epidemiol. 2005;20(1):67-71.

19. Harakeh S, Jariwalla RJ. Comparative study of the anti-HIV activities of ascorbate and thiol-containing reducing agents in chro- nically HIV-infected cells. Am J Clin Nutr. 1991 Dec;54(6 Suppl):1231S-5S.

20. Muller F, Svardal AM, Nordoy I, et al. Virological and immunological effects of antioxidant treatment in patients with HIV infec- tion. Eur J Clin Invest. 2000 Oct;30(10):905-14.

21. Rivas CI, Vera JC, Guaiquil VH, et al. Increased uptake and accumulation of vitamin C in human immunodeficiency virus 1- infected hematopoietic cell lines. J Biol Chem. 1997 Feb

22. Chambers JC, McGregor A, Jean-Marie J, Obeid OA, Kooner JS. Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy. Circulation. 1999 Mar 9;99(9):1156-60.

23. Plotnick GD, Corretti MC, Vogel RA. Effect of antioxidant vitamins on the transient impairment of endothelium-dependent bra- chial artery vasoactivity following a single high-fat meal. JAMA. 1997 Nov 26;278(20):1682-6.

24. Kinugawa S, Post H, Kaminski PM, et al. Coronary microvascular endothelial stunning after acute pressure overload in the cons- cious dog is caused by oxidant processes: the role of angiotensin II type 1 receptor and NAD(P)H oxidase. Circulation. 2003 Dec 9;108(23):2934-40.

25. Tousoulis D, Xenakis C, Tentolouris C, et al. Effects of vitamin C on intracoronary L-arginine dependent coronary vasodilatation in patients with stable angina. Heart. 2005 Oct;91(10):1319-23.

26. Katayama Y, Shige H, Yamamoto A, Hirata F, Yasuda H. Oral vitamin C ameliorates smoking-induced arterial wall stiffness in healthy volunteers. J Atheroscler Thromb. 2004;11(6):354-7.

27. Schindler TH, Nitzsche EU, Munzel T, et al. Coronary vasoregulation in patients with various risk factors in response to cold pressor testing: contrasting myocardial blood flow responses to short- and long-term vitamin C administration. J Am Coll Cardiol. 2003 Sep 3;42(5):814-22.

28. Varadharaj S, Steinhour E, Hunter MG, et al. Vitamin C-induced activation of phospholipase D in lung microvascular endothelial cells: Regulation by MAP kinases. Cell Signal. 2006 Sep;18(9):1396-407.

29. Nam CM, Oh KW, Lee KH, et al. Vitamin C intake and risk of ischemic heart disease in a population with a high prevalence of smoking. J Am Coll Nutr. 2003 Oct;22(5):372-8.

30. Knekt P, Ritz J, Pereira MA, et al. Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. Am J Clin Nutr. 2004 Dec;80(6):1508-20.

31. Osganian SK, Stampfer MJ, Rimm E, et al. Vitamin C and risk of coronary heart disease in women. J Am Coll Cardiol. 2003 Jul 16;42(2):246-52.

32. Nyyssonen K, Parviainen MT, Salonen R, Tuomilehto J, Salonen JT. Vitamin C deficiency and risk of myocardial infarction: prospective population study of men from eastern Finland. BMJ. 1997 Mar 1;314(7081):634-8.

33. Lopes C, Von HP, Ramos E, et al. Diet and risk of myocardial infarction. A case-control community-based study. Acta Med Port. 1998 Apr;11(4):311-7.

34. Riemersma RA, Carruthers KF, Elton RA, Fox KA. Vitamin C and the risk of acute myocardial infarction. Am J Clin Nutr. 2000 May;71(5):1181-6.

35. Jaxa-Chamiec T, Bednarz B, Drozdowska D, et al. Antioxidant effects of combined vitamins C and E in acute myocardial infarc- tion. The randomized, double-blind, placebo controlled, multicenter pilot Myocardial Infarction and VITamins (MIVIT) trial. Kardiol Pol. 2005 Apr;62(4):344-50.

36. Senthil S, Veerappan RM, Ramakrishna RM, Pugalendi KV. Oxidative stress and antioxidants in patients with cardiogenic shock complicating acute myocardial infarction. Clin Chim Acta. 2004 Oct;348(1-2):131-7.

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40. Gasparetto C, Malinverno A, Culacciati D, et al. Antioxidant vitamins reduce oxidative stress and ventricular remodeling in pati- ents with acute myocardial infarction. Int J Immunopathol Pharmacol. 2005 Jul;18(3):487-96.

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43. Liu P, Xu B, Cavalieri TA, Hock CE. Attenuation of antioxidative capacity enhances reperfusion injury in aged rat myocardium after MI/R. Am J Physiol Heart Circ Physiol. 2004 Dec;287(6):H2719-27.

44. Baltalarli A, Ozcan V, Ferda B, et al. Ascorbic acid (vitamin C) and iloprost attenuate the lung injury caused by ische- mia/reperfusion of the lower extremities of rats. Ann Vasc Surg. 2006 Jan;20(1):49-55.

45. Eguchi M, Monden K, Miwa N. Role of MAPK phosphorylation in cytoprotection by pro-vitamin C against oxidative stress- induced injuries in cultured cardiomyoblasts and perfused rat heart. J Cell Biochem. 2003 Oct 1;90(2):219-26.

46. Saitoh Y, Miwa N. Cytoprotection of vascular endotheliocytes by phosphorylated ascorbate through suppression of oxidative stress that is generated immediately after post-anoxic reoxygenation or with alkylhydroperoxides. J Cell Biochem. 2004 Nov 1;93(4):653-63.

47. Padayatty SJ, Riordan HD, Hewitt SM, Katz A, Hoffer LJ, Levine M. Intravenously administered vitamin C as cancer therapy: three cases. CMAJ. 2006 Mar 28;174(4):937-42.

48. McCarty MF. Adjuvant strategies for prevention of glomerulosclerosis. Med Hypotheses. 2006 Jul 5; [Epub ahead of print]

49. Shidfar F, Baghai N, Keshavarz A, Ameri A, Shidfar S. Comparison of plasma and leukocyte vitamin C status between asthmatic and healthy subjects. East Mediterr Health J. 2005 Jan-Mar;11(1-2):87-95.

50. Prynne CJ, Mishra GD, O’Connell MA, et al. Fruit and vegetable intake and bone mineral status: a cross sectional study in 5 age and sex cohorts. Am J Clin Nutr. 2006 Jun;83(6):1420-8.

51. Katsuyama H, Sunami S, Fukunaga M. Influence of nutrients intake on bone turnover markers. Clin Calcium. 2005 Sept;15(9):1529-34.

52. Gaby AR. Natural remedies for Herpes simplex. Altern Med Rev. 2006 Jun;11(2):93-101.

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54. Korantzopoulos P, Kolettis TM, Kountouris E, et al. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation. Int J Cardiol. 2005 Jul 10;102(2):321-6.

55. Demirbag R, Yilmaz R, Erel O, et al. The relationship between potency of oxidative stress and severity of dilated cardiomyo- pathy. Can J Cardiol. 2005 Aug;21(10):851-5.

56. Freeman LM, Rush JE, Milbury PE, Blumberg JB. Antioxidant status and biomarkers of oxidative stress in dogs with congestive heart failure. J Vet Intern Med. 2005 Jul;19(4):537-41.

57. Monahan KD, Eskurza I, Seals DR. Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men. Am J Physiol Heart Circ Physiol. 2004 Jun;286(6):H2113-7.

58. Bassenge E, Fink N, Skatchkov M, Fink B. Dietary supplement with vitamin C prevents nitrate tolerance. J Clin Invest. 1998 Jul 1;102(1):67-71.

59. Watanabe H, Kakihana M, Ohtsuka S, Sugishita Y. Randomized, double-blind, placebo-controlled study of the preventive effect of supplemental oral vitamin C on attenuation of development of nitrate tolerance. J Am Coll Cardiol. 1998 May;31(6):1323-9.

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61. Canoy D, Wareham N, Welch A, et al. Plasma ascorbic acid concentrations and fat distribution in 19,068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study. Am J Clin Nutr. 2005 Dec;82(6):1203- 9.

62. Tsimikas S, Brilakis ES, Miller ER, et al. Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease. N Engl J Med. 2005 Jul 7;353(1):46-57.

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64. Nagyova A, Krajcovicova-Kudlackova M, Horska A, et al. Lipid peroxidation in men after dietary supplementation with a mixtu- re of antioxidant nutrients. Bratisl Lek Listy. 2004;105(7-8):277-80.

65. Cobbold CA, Sherratt JA, Maxwell SR. Lipoprotein oxidation and its significance for atherosclerosis: a mathematical approach. Bull Math Biol. 2002 Jan;64(1):65-95.

66. Ginter E. Ascorbic acid in cholesterol and bile acid metabolism. Ann NY Acad Sci. 1975 Sept 30;258:410-21.

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68. Turley SD, West CE, Horton BJ. The role of ascorbic acid in the regulation of cholesterol metabolism and in the pathogenesis of artherosclerosis. Atherosclerosis. 1976 Jul;24(1-2):1-18.

69. Kaul D, Baba MI. Genomic effect of vitamin ‘C’ and statins within human mononuclear cells involved in atherogenic process. Eur J Clin Nutr. 2005 Aug;59(8):978-81.

70. Vinson JA, Jang J. In vitro and in vivo lipoprotein antioxidant effect of a citrus extract and ascorbic acid on normal and hypercho- lesterolemic human subjects. J Med Food. 2001;4(4):187-92.

71. Benade L, Howard T, Burk D: Synergystic killing of Ehrlich ascites carcinoma cells by ascorbate and 3-amino-1,2,4-triazole. On- cology, 1969;23:33-43

72. Maramag C, Menon M, Balaji KC, Reddy PG, laxmanan S: Effect of vitamin C on prostate cancer cells in vitro: effect on cell number, viability, and DNA synthesis. Prostate,1997; 32:188-95

73. Riordan NH, et al: Intravenous ascorbate as atumor cytotoxic chemotherapeutic agent. Med. Hypoth,1994;9:207-213

74. Riordan n, Jackson JA, Riordan HD: Intravenous vitamin C in a terminal cancer patient. J. Orthomol Med, 1996;11:80-82

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